Cinque Terre

阮丽芳

来源: 责任编辑: 发布:2015-11-05 点击量:






职称 教授

学位 博士

邮箱  ruanlifang@mail.hzau.edu.cn

研究方向 植物细菌性病害致病机制及防控


教育经历

1992.09-1999.07狗万app苹果未受信任 ,理学学士/硕士

1999.09-2002.07武汉大学生命科学院,理学博士

主要职历

2002.9-2004.7 华中农业大学博士后

2004.7-2015.12 狗万app苹果未受信任 副教授

2016.1-至今 狗万app苹果未受信任 教授

2003.7-2004.2 香港理工大学research associate

2007.12-2009.6 加拿大阿尔伯塔大学 博士后

科研成果

科研方向

水稻黄单胞菌致病机理的研究:包括水稻黄单胞菌胞内致病相关调控机理;水稻黄单胞菌与宿主的互作;水稻黄单胞菌进化及流行病学规律研究。针对经济作物番茄,烟草青枯病的研究:拟通过研究致病菌雷尔氏青枯胞外致病蛋白与宿主的互作,揭示致病机理,进一步通过植物改良获取青枯病抗性品种。不同品种番茄根际微生物组的研究,拟通过揭示抗性番茄根际微生物组成,利用可培养微生物组,构建人工合成微生物,用于青枯的生物防治。同时通过全国范围内取样,普查番茄,烟草青枯病的发生,调查青枯病发生与根际微生物组的内在联系。


主要代表论文(仅包括第一和通讯作者) 

1.Dehong Zheng, Huihui Wang, Hao Zhong, Wenli Ke, Huifeng Hu, Ming Sun, Lifang Ruan* Elucidation of the Pathogenicity-Associated Regulatory Network in Xanthomonas oryzae pv. Oryzae mSystems 2021 Mar 9;6(2):e00789-20.

doi: 10.1128/mSystems.00789-20. Impact factor: 7.3

2. Yuqing Qin#, Gaobing Wu#, Yiming Guo, Da Ke, Jiakang Yin, Donglin Wang, Xuezhu Fan, Ziduo Liu, Lifang Ruan*, Yonggang Hu*,Engineered glyphosate oxidase coupled to spore-based chemiluminescence system for glyphosate detection Anal Chim Acta. 2020 Oct 9;1133:39-47. Impact factor: 5.5

3. Jiakang Yina, Youfeng Yua, Ziliang Zhanga, Lingling Chen, Lifang Ruan* Enrichment of potentially beneficial bacteria from the consistent microbial community confers canker resistance on tomato. Microbiol Res. 2020 (234):126446 Impact factor: 3.9

4. Zheng D, Zeng Z, Xue B, Deng Y, Sun M, Tang YJ, Ruan L.* Bacillus thuringiensis produces the lipopeptide thumolycin to antagonize microbes and nematodes. Microbiol Res. 2018 (215):22-28. Impact factor: 3.9

5. Activation of PhoBR under phosphate-rich conditions reduces the virulence of Xanthomonas oryzae pv. oryzae.Zheng D, Xue B, Shao Y, Yu H, Yao X, Ruan L.* Mol Plant Pathol. 2018(19):2066-2076. Impact factor: 4.6

6. Wang J, Guo J, Wang S, Zeng Z, Zheng D, Yao X, Yu H, Ruan L* (2017) The global strategy employed by Xanthomonas oryzae pv. oryzae to conquer low-oxygen tension. J Proteomics 161: 68-77 Impact facter3.9

7. Zheng D.H., Yao X.Y., Duan M., Luo Y.F., Liu B., Qi P.Y., Sun M., Ruan L.F.* (2016). “Two overlapping twocomponent systems in Xanthomonas oryzae pv. oryzae contribute to full fitness in rice by regulating virulence factors expression”. Sci. Rep.doi:10.1038/srep22768 , Impact factor: 5.578

8. Ruan, L. F., N. Crickmore, D. H. Peng and M. Sun (2015) "Are nematodes a missing link in the confounded ecology of the entomopathogen Bacillus thuringiensis?" Trends in Microbiology 23(6): 341-346.Impact facter9.2

9. Ruan, L., N. Crickmore and M. Sun (2015) "Is There Sufficient Evidence to Consider Bacillus thuringiensis a Multihost Pathogen? Response to Loguercio and Argôlo-Filho." Trends in Microbiology 23(10): 587. Impact facter9.2)

10. Ruan, L.*, H. Wang, G. Cai, D. Peng, H. Zhou, J. Zheng, L. Zhu, X. Wang, H. Yu, S. Li, C. Geng and M. Sun (2015) "A two-domain protein triggers heat shock pathway and necrosis pathway both in model plant and nematode." Environ Microbiol. (Impact facter6.3)

11. Ruan, L. F., A. Pleitner, M. G. Ganzle and L. M. McMullen (2011). "Solute Transport Proteins and the Outer Membrane Protein NmpC Contribute to Heat Resistance of Escherichia coli AW1.7." Appl and Environ Microbiol 77(9): 2961-2967.

12. Liu, X. Y., L. F. Ruan, Z. F. Hu, D. H. Peng, S. Y. Cao, Z. N. Yu, Y. Liu, J. S. Zheng and M. Sun (2010). "Genome-wide Screening Reveals the Genetic Determinants of an Antibiotic Insecticide in Bacillus thuringiensis." J Biol Chem 285(50): 39191-39200.(共同第一)


发明授权专利:

1. 阮丽芳;孙明;彭东海;王慧慧;蔡格(2019)苏云金芽胞杆菌YBT-1520中的杀线虫蛋白NEL的应用。ZL 201510701737.0
2. 阮丽芳,孙明,刘凤侠,杨文君,彭东海(2013)高产黑色素的苏云金芽胞杆突变株BMB181。中国专利号:ZL200910060530.4

3. 阮丽芳,孙明,彭东海,王慧慧,蔡格 (2019)苏云金芽胞杆菌YBT-1520中的杀线虫蛋白NEL的应用。中国专利号:ZL 201510701737.0
4. 孙明,彭东海,阮丽芳,柴陆军,鞠守勇,王奋山 (2014) 对南方根结线虫具有杀虫增效作用的蛋白组合物Cry6A/Cry55A及应用, 中国专利号:
ZL201110376796.7

5. 孙明,喻子牛,阮丽芳,陈守文,刘晓艳,彭东海(2010)合成苏云金素的基因簇。中国专利号:ZL200910060530.4




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